The CLOTSTOP® Principle
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In a study by Pearce et al. 1 the clotting
characteristics of standard silicone wound drains
and silicone closed wound drains
coated with CLOTSTOP® were compared.
Both the standard and CLOTSTOP® coated silicone drains
were filled with equal amounts of whole blood. The whole blood remained in the drains for an equal period of time. suction was apllied and slowly increased until the clots started moving and were extracted from the drain. The exact evacuation pressure to extract the clot from the drain was recorded.
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Results: An average pressure of 26 mm/Hg (range 15 - 45 mm/Hg) was required to extract the blood from the CLOTSTOP® drains.
An average pressure of 151 mm/Hg (range 135 - 170 mm/Hg)was required to extract the blood clots from the uncoated silicone drains.
This study is clinically significant because the leading commercially available 100ml closed wound rexervoirs reported to generate a maximum pressure of 90 mm/Hg after 10ml drainage.
Therefore, it can be concluded that the standard 100ml reservoirs could READILY EXTRACT CLOTS FROM THE CLOTSTOP®COATED DRAIN but would be INEFFECTIVE in removing clots from standard, uncoated, silicione, closed wound drains.
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1 Pearce, Scott C., et al.: Evaluation af a New Hydrogel Coating for Drainage Tubes; The American Journal of Surgery, Vol. 148, Nov. 1984, pp 687-691 |